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PIM1

pim-1 oncogene

Sinónimos:
PIM
Especie:
ID UniProtKB:
ID del gen:
  • Human(5292) Summary: The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810).[provided by RefSeq, Aug 2011]
  • Mouse(18712) proviral integration site 1
  • Rat(24649) pim-1 oncogene
  • Zebrafish(58054) pim-1 oncogene
  • domestic cat(493888) pim-1 oncogene
  • Horse(100053898) pim-1 oncogene
  • chicken(100858838) pim-1 oncogene
  • dog(481772) pim-1 oncogene
  • cow(281402) pim-1 oncogene
  • sheep(100272002) pim-1 oncogene
  • domestic guinea pig(100724588) pim-1 oncogene
  • naked mole-rat(101706236) pim-1 oncogene

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Monoclonal Anti-PIM1 antibody produced in mouse, clone 6A2, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
immunofluorescence

immunohistochemistry
ANTI-PIM1 antibody produced in mouse, clone 2C9, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-PIM1, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat, sheep
Aplicación
western blot
Anti-phospho-Pim-1 (pTyr309) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
western blot
ANTI-PIM1 antibody produced in mouse, clone 1C12, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
western blot

Proteins

Referencia del producto
Descripción
Especie
PIM1, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human PIM1,
Especie
human
MISSION® esiRNA, targeting mouse Pim1,
Especie
mouse