OBSCN
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Sinónimos:
ARHGEF30, UNC89
Especie:
Human OBSCN (84033), Mouse Obscn (380698), Rat Obscn (338458), Zebrafish obscn (445358), domestic cat OBSCN (101101539), cow OBSCN (537193), dog OBSCN (482206), chicken OBSCN (420395), sheep OBSCN (101121853), domestic guinea pig Obscn (100727808)
ID UniProtKB:
ID del gen:
- Human(84033) Summary: The obscurin gene spans more than 150 kb, contains over 80 exons and encodes a protein of approximately 720 kDa. The encoded protein contains 68 Ig domains, 2 fibronectin domains, 1 calcium/calmodulin-binding domain, 1 RhoGEF domain with an associated PH domain, and 2 serine-threonine kinase domains. This protein belongs to the family of giant sacromeric signaling proteins that includes titin and nebulin, and may have a role in the organization of myofibrils during assembly and may mediate interactions between the sarcoplasmic reticulum and myofibrils. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
- Mouse(380698) obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
- Rat(338458) obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
- Zebrafish(445358) obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
- domestic cat(101101539) obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
- cow(537193) obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
- dog(482206) obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
- chicken(420395) obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
- sheep(101121853) obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
- domestic guinea pig(100727808) obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
- naked mole-rat(101701039) obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Obscurin Antibody, clone 5H10A, clone 5H10A, from mouse,
Reactividad de especies
human, mouse, rat
Aplicación
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-OBSCN antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab2,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-OBSCN antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-C1ORF145 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry