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MilliporeSigma

MTOR

mechanistic target of rapamycin (serine/threonine kinase)

Sinónimos:
FRAP, FRAP1, FRAP2, RAFT1, RAPT1
Especie:
Human MTOR (2475), Mouse Mtor (56717), Rat Mtor (56718), Zebrafish mtor (324254), cow MTOR (100139219), Horse MTOR (100051341), domestic cat MTOR (101098152), dog MTOR (478232), fruit fly Mtor (36264), chicken MTOR (419455) ...Más
ID UniProtKB:
P42345, Q4LE76, Q5TER1, Q6LE87, Q96QG3, Q9Y4I3
ID del gen:
  • Human(2475) Summary: The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq, Sep 2008]
  • Mouse(56717) mechanistic target of rapamycin (serine/threonine kinase)
  • Rat(56718) mechanistic target of rapamycin (serine/threonine kinase)
  • Zebrafish(324254) mechanistic target of rapamycin (serine/threonine kinase)
  • cow(100139219) mechanistic target of rapamycin (serine/threonine kinase)
  • Horse(100051341) mechanistic target of rapamycin (serine/threonine kinase)
  • domestic cat(101098152) mechanistic target of rapamycin (serine/threonine kinase)
  • dog(478232) mechanistic target of rapamycin (serine/threonine kinase)
  • fruit fly(36264) Megator
  • chicken(419455) mechanistic target of rapamycin (serine/threonine kinase)
  • Domestic Rabbit(100356164) mechanistic target of rapamycin (serine/threonine kinase)
  • naked mole-rat(101725626) mechanistic target of rapamycin (serine/threonine kinase)
  • domestic guinea pig(100724938) mechanistic target of rapamycin (serine/threonine kinase)
  • Goat(100860902) mechanistic target of rapamycin (serine/threonine kinase)
  • sheep(100271659) mechanistic target of rapamycin (serine/threonine kinase)

Custom & Knockdown Gene Products

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  • Custom Gene Products

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
OP97
Anti-mTOR/FRAP (Ab-2) Mouse mAb (22C2), liquid, clone 22C2, Calbiochem®,
Reactividad de especies
human
Aplicación
SAB4504476
Anti-phospho-mTOR (pSer2448) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunohistochemistry
western blot
09-213
Anticuerpo anti-fosfo-mTOR (Ser2448), Upstate®, from rabbit,
Reactividad de especies
human
Aplicación
western blot
05-1592
Anti-mTOR Antibody, clone 21D8.2, clone 2ID8.2, from mouse,
Reactividad de especies
human, mouse
Aplicación
immunocytochemistry
western blot
SAB4301526
Anti-phospho-mTOR (pSer2481) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
western blot

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
SML0120
Perhexiline maleate salt, ≥98% (HPLC),
Especie
human
PZ0235
PF-04691502, ≥98% (HPLC),
Especie
human

Proteins

Referencia del producto
Descripción
Especie
14-770-M
mTOR (1362-end) Protein, active, 10 µg, Active, N-terminal FLAG-tagged, recombinant, human mTOR, amino acids 1362-end, for use in Kinase Assays.,
Especie
human
SRP0364
mTOR/Raptor/MLST8 human, recombinant, expressed in baculovirus infected Sf9 cells, ≥50% (SDS-PAGE),
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
EHU101641
MISSION® esiRNA, targeting human MTOR,
Especie
human