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MilliporeSigma

DDB2

damage-specific DNA binding protein 2, 48kDa

Sinónimos:
DDBB, UV-DDB2
Especie:
ID UniProtKB:
ID del gen:
  • Human(1643) Summary: This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. [provided by RefSeq, Jul 2008]
  • Mouse(107986) damage specific DNA binding protein 2
  • Rat(100362121) damage specific DNA binding protein 2
  • Zebrafish(100004133) damage-specific DNA binding protein 2
  • chicken(423185) damage-specific DNA binding protein 2, 48kDa
  • Thale Cress(835990) DNA damage-binding protein 2
  • cow(519357) damage-specific DNA binding protein 2, 48kDa
  • Horse(100051180) damage-specific DNA binding protein 2, 48kDa
  • domestic cat(101092211) damage-specific DNA binding protein 2, 48kDa
  • dog(483626) damage-specific DNA binding protein 2, 48kDa
  • sheep(101116344) damage-specific DNA binding protein 2, 48kDa
  • Domestic Rabbit(100352386) damage-specific DNA binding protein 2, 48kDa
  • naked mole-rat(101715591) damage-specific DNA binding protein 2, 48kDa
  • domestic guinea pig(100726538) damage-specific DNA binding protein 2, 48kDa

Custom & Knockdown Gene Products

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-DDB2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
Anti-DDB2 antibody produced in rabbit, ,
Reactividad de especies
human, mouse
Aplicación
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Ddb2,
Especie
mouse
MISSION® esiRNA, targeting human DDB2,
Especie
human