DAG1
dystroglycan 1 (dystrophin-associated glycoprotein 1)
Sinónimos:
156DAG, A3a, AGRNR, DAG, MDDGC7, MDDGC9
Especie:
Human DAG1 (1605), Mouse Dag1 (13138), Rat Dag1 (114489), sheep DAG1 (101103515), Domestic Rabbit DAG1 (100009278), naked mole-rat Dag1 (101714190), domestic guinea pig Dag1 (100734382), Zebrafish dag1 (286829), cow DAG1 (281439), Horse DAG1 (100053150) ...Más
ID UniProtKB:
ID del gen:
- Human(1605) Summary: Dystroglycan is a laminin binding component of the dystrophin-glycoprotein complex which provides a linkage between the subsarcolemmal cytoskeleton and the extracellular matrix. Dystroglycan 1 is a candidate gene for the site of the mutation in autosomal recessive muscular dystrophies. The dramatic reduction of dystroglycan 1 in Duchenne muscular dystrophy leads to a loss of linkage between the sarcolemma and extracellular matrix, rendering muscle fibers more susceptible to necrosis. Dystroglycan also functions as dual receptor for agrin and laminin-2 in the Schwann cell membrane. The muscle and nonmuscle isoforms of dystroglycan differ by carbohydrate moieties but not protein sequence. Alternative splicing results in multiple transcript variants all encoding the same protein.[provided by RefSeq, Apr 2010]
- Mouse(13138) dystroglycan 1
- Rat(114489) dystroglycan 1 (dystrophin-associated glycoprotein 1)
- sheep(101103515) dystroglycan 1 (dystrophin-associated glycoprotein 1)
- Domestic Rabbit(100009278) dystroglycan 1 (dystrophin-associated glycoprotein 1)
- naked mole-rat(101714190) dystroglycan 1 (dystrophin-associated glycoprotein 1)
- domestic guinea pig(100734382) dystroglycan 1 (dystrophin-associated glycoprotein 1)
- Zebrafish(286829) dystroglycan 1
- cow(281439) dystroglycan 1 (dystrophin-associated glycoprotein 1)
- Horse(100053150) dystroglycan 1 (dystrophin-associated glycoprotein 1)
- domestic cat(100174781) dystroglycan 1 (dystrophin-associated glycoprotein 1)
- dog(476623) dystroglycan 1 (dystrophin-associated glycoprotein 1)
- chicken(100049058) dystroglycan 1 (dystrophin-associated glycoprotein 1)
- Thale Cress(825358) Dof zinc finger protein DOF3.7
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anticuerpo anti-α-distroglucano, clon VIA4-1, culture supernatant, clone VIA4-1, Upstate®,
Reactividad de especies
canine, guinea pig, human, mouse, rabbit, rat
Aplicación
immunohistochemistry
western blot
western blot
Anti-α-Dystroglycan Antibody, ,
Reactividad de especies
canine, guinea pig, human, mouse, rabbit, rat
Aplicación
Anti-TROP2 Antibody, clone TrMab-29, ,
Reactividad de especies
human
Aplicación
flow cytometry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-α-Dystroglycan Antibody, clone VIA4-1 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
canine, guinea pig, human, mouse, rabbit, rat
Aplicación
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Cranin Antibody, aa572-604 of human sequence, clone 6C1, ascites fluid, clone 6C1, Chemicon®,
Reactividad de especies
xenopus, chicken, human, mouse, rat, sheep
Aplicación
ELISA
immunocytochemistry
immunohistochemistry
immunocytochemistry
immunohistochemistry