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MilliporeSigma

CHRNB3

cholinergic receptor, nicotinic, beta 3 (neuronal)

Sinónimos:
Especie:
Human CHRNB3 (1142), Mouse Chrnb3 (108043), Rat Chrnb3 (171131), chicken CHRNB3 (395604), cow CHRNB3 (521702), Horse CHRNB3 (100054095), dog CHRNB3 (482837), domestic cat CHRNB3 (101098624), sheep CHRNB3 (101122833), Domestic Rabbit CHRNB3 (100355898) ...Más
ID UniProtKB:
Q05901, Q15827
ID del gen:
  • Human(1142) Summary: The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are (hetero)pentamers composed of homologous subunits. The subunits that make up the muscle and neuronal forms of nAChRs are encoded by separate genes and have different primary structure. There are several subtypes of neuronal nAChRs that vary based on which homologous subunits are arranged around the central channel. They are classified as alpha-subunits if, like muscle alpha-1 (MIM 100690), they have a pair of adjacent cysteines as part of the presumed acetylcholine binding site. Subunits lacking these cysteine residues are classified as beta-subunits (Groot Kormelink and Luyten, 1997 [PubMed 9009220]
  • Mouse(108043) cholinergic receptor, nicotinic, beta polypeptide 3
  • Rat(171131) cholinergic receptor, nicotinic, beta 3 (neuronal)
  • chicken(395604) cholinergic receptor, nicotinic, beta 3 (neuronal)
  • cow(521702) cholinergic receptor, nicotinic, beta 3 (neuronal)
  • Horse(100054095) cholinergic receptor, nicotinic, beta 3 (neuronal)
  • dog(482837) cholinergic receptor, nicotinic, beta 3 (neuronal)
  • domestic cat(101098624) cholinergic receptor, nicotinic, beta 3 (neuronal)
  • sheep(101122833) cholinergic receptor, nicotinic, beta 3 (neuronal)
  • Domestic Rabbit(100355898) cholinergic receptor, nicotinic, beta 3 (neuronal)
  • naked mole-rat(101706291) cholinergic receptor, nicotinic, beta 3 (neuronal)
  • domestic guinea pig(100723424) cholinergic receptor, nicotinic, beta 3 (neuronal)

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Small Molecule - Agonist

Referencia del producto
Descripción
Especie
D1260
Decamethonium bromide, crystalline,
Especie
human
D5891
1,1-Dimethyl-4-phenylpiperazinium iodide, ≥98% (TLC or titration),
Especie
human, rat

Small Molecule - Antagonist

Referencia del producto
Descripción
Especie
M9020
Mecamylamine hydrochloride, ,
Especie
human
D5891
1,1-Dimethyl-4-phenylpiperazinium iodide, ≥98% (TLC or titration),
Especie
human, rat
K3375
Kynurenic acid, ≥98%,
Especie
rat, human

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
HPA045555
Anti-CHRNB3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
SAB2500239
Anti-CHRNB3 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
western blot

Small Molecule - Blocker

Referencia del producto
Descripción
Especie
T2265
Tetraethylammonium chloride, ≥98% (titration),
Especie
human
H0879
Hexamethonium bromide, ,
Especie
human
H2138
Hexamethonium chloride, solid (hygroscopic),
Especie
human
K3375
Kynurenic acid, ≥98%,
Especie
rat, human

Proteins

Referencia del producto
Descripción
Especie
B3303
Buserelin acetate salt, ≥90% (HPLC),
Especie
rat