CASP9
caspase 9, apoptosis-related cysteine peptidase
Sinónimos:
APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56
Especie:
Human CASP9 (842), Mouse Casp9 (12371), Rat Casp9 (58918), Zebrafish casp9 (492763), dog CASP9 (487432), Horse CASP9 (100054331), cow CASP9 (100140945), domestic cat CASP9 (768260), chicken CASP9 (426970), domestic guinea pig Casp9 (100714954) ...Más
ID UniProtKB:
ID del gen:
- Human(842) Summary: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
- Mouse(12371) caspase 9
- Rat(58918) caspase 9, apoptosis-related cysteine peptidase
- Zebrafish(492763) caspase 9, apoptosis-related cysteine protease
- dog(487432) caspase 9, apoptosis-related cysteine peptidase
- Horse(100054331) caspase 9, apoptosis-related cysteine peptidase
- cow(100140945) caspase 9, apoptosis-related cysteine peptidase
- domestic cat(768260) caspase 9, apoptosis-related cysteine peptidase
- chicken(426970) caspase 9, apoptosis-related cysteine peptidase
- domestic guinea pig(100714954) caspase 9, apoptosis-related cysteine peptidase
- naked mole-rat(101702898) caspase 9, apoptosis-related cysteine peptidase
- sheep(101110953) caspase 9, apoptosis-related cysteine peptidase
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siRNA
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-CASP9 (Cleaved-Asp330), C-Terminal antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human
Aplicación
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Caspase 9 antibody,Mouse monoclonal, clone CAS9, purified from hybridoma cell culture,
Reactividad de especies
human
Aplicación
ELISA
microarray
western blot
microarray
western blot
Anti-Caspase 9 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human
Aplicación
western blot
Anti-Caspase-9 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-Caspase 9 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Small Molecule - Inhibitor
Kits
Referencia del producto
Descripción
Especie
Caspase 9 Colorimetric Activity Assay Kit, LEHD, Caspase-9 Colorimetric Activity Assay Kits provide a simple & convenient means for assaying the activity of caspases that recognize the LEHD.,
Especie
human
Caspase 9 Colorimetric Activity Assay Kit, LEHD, Caspase-9 Colorimetric Activity Assay Kits provide a simple & convenient means for assaying the activity of caspases that recognize the LEHD.,
Especie
human
Proteins
Referencia del producto
Descripción
Especie
Caspase 9 human, ≥90% (SDS-PAGE), recombinant, expressed in E. coli (C-terminal histidine-tagged), buffered aqueous solution, >2,000 units/mg protein,
Especie
human
esiRNA
Small Molecule - Substrate
Referencia del producto
Descripción
Especie
N-Acetyl-Leu-Glu-His-Asp-7-amido-4-trifluoromethylcoumarin, ≥95% (HPLC), powder,
Especie
mouse, rat, human