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Merck

BAX

BCL2-associated X protein

Sinónimos:
BCL2L4
Especie:
Human BAX (581), Mouse Bax (12028), Rat Bax (24887), naked mole-rat Bax (101713575), domestic guinea pig Bax (100730890), Goat BAX (100846984), sheep BAX (443059), dog BAX (403523), domestic cat BAX (493837), cow BAX (280730)
ID UniProtKB:
Q07812, A8K4W1, P55269, Q07814, Q07815, Q8WZ49, Q9NR76, Q9NYG7
ID del gen:
  • Human(581) Summary: The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(12028) BCL2-associated X protein
  • Rat(24887) Bcl2-associated X protein
  • naked mole-rat(101713575) BCL2-associated X protein
  • domestic guinea pig(100730890) BCL2-associated X protein
  • Goat(100846984) BCL2-associated X protein
  • sheep(443059) BCL2-associated X protein
  • dog(403523) BCL2-associated X protein
  • domestic cat(493837) BCL2-associated X protein
  • cow(280730) BCL2-associated X protein

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
ABC11
Anti-Bax (NT) Antibody, from rabbit,
Reactividad de especies
bovine, canine, chimpanzee, feline, human, rhesus monkey
Aplicación
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
MAB4601
Anti-Bax Antibody, NT, aa3-16 hBax protein, clone 2D2, clone 2D2, Chemicon®, from mouse,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
western blot
ZRB1103
Anti-Bax Antibody, clone 1C7, ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human
Aplicación
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
SAB5700071
Anti-BAX antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
immunoprecipitation (IP)
western blot
WH0000581M1
Monoclonal Anti-BAX antibody produced in mouse, clone 1F5-1B7, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
immunofluorescence
immunohistochemistry
proximity ligation assay
western blot

Cell Lines

Referencia del producto
Descripción
Especie
CLLS1006
SW48 Cells BAX -/-, ,
Especie
human
CLLS1001
DLD1 Cells BAX -/-, ,
Especie
human
CLLS1005
DLD1 Cells BAX/BAK (-/-,-/-), ,
Especie
human
CLLS1011
SW48 Cells BAX/BAK (-/-,-/-), ,
Especie
human

Proteins

Referencia del producto
Descripción
Especie
SRP5166
BAX, GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
EHU069421
MISSION® esiRNA, targeting human BAX,
Especie
human