APC
adenomatous polyposis coli
Sinónimos:
BTPS2, DP2, DP2.5, DP3, GS, PPP1R46
Especie:
Human APC (324), Mouse Apc (11789), Rat Apc (24205), sheep APC (101104664), domestic guinea pig Apc (100723694), naked mole-rat Apc (101704055), Zebrafish apc (386762), fruit fly Apc (44642), cow APC (533233), Horse APC (100064431) ...Más
ID UniProtKB:
ID del gen:
- Human(324) Summary: This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq, Jul 2008]
- Mouse(11789) adenomatosis polyposis coli
- Rat(24205) adenomatous polyposis coli
- sheep(101104664) adenomatous polyposis coli
- domestic guinea pig(100723694) adenomatous polyposis coli
- naked mole-rat(101704055) adenomatous polyposis coli
- Zebrafish(386762) adenomatosis polyposis coli
- fruit fly(44642) APC-like
- cow(533233) adenomatous polyposis coli
- Horse(100064431) adenomatous polyposis coli
- domestic cat(101096138) adenomatous polyposis coli
- dog(479139) adenomatous polyposis coli
- chicken(415607) adenomatous polyposis coli
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anticuerpo anti-APC, clon CC-1, clone CC-1, from mouse,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-APC (Ab-1) Mouse mAb (FE9), liquid, clone FE9, Calbiochem®,
Reactividad de especies
human, mouse, rat
Aplicación
Anti-APC antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-APC (C-terminal) antibody produced in rabbit, ~1.0 mg/mL, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-APC Antibody, clone FE9, clone FE9, from mouse,
Reactividad de especies
human
Aplicación
western blot
Cell Lines
Referencia del producto
Descripción
Especie