P7561

Phentolamine methanesulfonate salt

≥98% (TLC), powder

• Synonym(s): 2-(N-[m-Hydroxyphenyl]-p-toluidinomethyl)imidazoline
• Linear Formula: C₁₇H₁₉N₃O · CH₃SO₃H
• CAS Number: 65-28-1
• Molecular Weight: 377.46
• EC Number: 200-604-6
• MDL number: MFCD00134201
• UNSPSC Code: 12352116
• PubChem Substance ID: 24277798
• NACRES: NA.77

Properties

• Quality Level: 200
• assay: ≥98% (TLC)
• form: powder
• color: white to off-white
• mp: 180-182 °C (lit.)
• solubility: ethanol: 26 mg/mL; H₂O: 50 mg/mL
• originator: Novartis
• SMILES string: CS(O)(=O)=O.Cc1ccc(cc1)N(CC2=NCCN2)c3cccc(O)c3
• InChI: 1S/C17H19N3O.CH4O3S/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15;1-5(2,3)4/h2-8,11,21H,9-10,12H2,1H3,(H,18,19);1H3,(H,2,3,4)
• InChI key: OGIYDFVHFQEFKQ-UHFFFAOYSA-N
• Gene Information: human ... ADRA1A(148) , ADRA1B(147) , ADRA1D(146) , ADRA2A(150) , ADRA2B(151) , ADRA2C(152)

Description

Biochem/physiol Actions

α-Adrenergic receptor antagonist; peripheral vasodilator.

Features and Benefits

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302,H315,H319,H335
• pcodes: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• ppe: dust mask type N95 (US), Eyeshields, Gloves