114278

(2-Chloroethoxy)benzene

98%

• Synonym(s): β-Chlorophenetole, 2-Chloroethyl phenyl ether
• Linear Formula: C₆H₅OCH₂CH₂Cl
• CAS Number: 622-86-6
• Molecular Weight: 156.61
• Beilstein/REAXYS Number: 971048
• EC Number: 210-757-0
• MDL number: MFCD00018946
• UNSPSC Code: 12352100
• PubChem Substance ID: 24847162
• NACRES: NA.22

Properties

• assay: 98%
• refractive index: n20/D 1.534 (lit.)
• bp: 97-98 °C/15 mmHg (lit.)
• density: 1.129 g/mL at 25 °C (lit.)
• functional group: chloro; phenoxy
• SMILES string: ClCCOc1ccccc1
• InChI: 1S/C8H9ClO/c9-6-7-10-8-4-2-1-3-5-8/h1-5H,6-7H2
• InChI key: VQUYNUJARXBNPK-UHFFFAOYSA-N

Description

Application

(2-Chloroethoxy)benzene is used in the coupling reaction of benzaldehyde, cinnamyltrimethylsilane and anisole in the synthesis of pseudo-symmetrical tamoxifen derivatives.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: 213.8 °F - closed cup
• flash_point_c: 101 °C - closed cup
• ppe: Eyeshields, Gloves, type ABEK (EN14387) respirator filter