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Merck

LC/MS Analysis of CYP2D6 Inhibitors on Ascentis® Express HILIC

LC/MS Analysis of CYP2D6 Inhibitors on Ascentis® Express HILIC application for HPLC

材料

分析柱

產品號碼
描述
訂價

Ascentis® Express HILIC, 2.7 μm HPLC色谱柱

2.7 μm particle size, L × I.D. 10 cm × 2.1 mm

標準品

產品號碼
描述
訂價

丙米嗪 盐酸盐

≥99% (TLC)

帕罗西汀 盐酸盐

United States Pharmacopeia (USP) Reference Standard

盐酸阿米替林

Pharmaceutical Secondary Standard; Certified Reference Material

氟西汀盐酸盐

Pharmaceutical Secondary Standard; Certified Reference Material

流動相成分

產品號碼
描述
訂價

甲酸铵

eluent additive for LC-MS, LiChropur, ≥99.0%

CONDITIONS

column

Ascentis Express HILlC, 10 cm x 2.1 mm I.D., 2.7 μm particles (53939-U)

mobile phase

5 mM ammonium formate in 2:98 (v/v) water:acetonitrile

flow rate

1.2 mL/min

column temp.

50 °C

detector

ESI(+), m/z 100-400

injection

0.5 μL

描述

分析報告

This application demonstrates the suitability of the Ascentis Express HILIC for the analysis of CYP2D6 Inhibitors.

法律資訊

Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany