- Re(CO)5Br-catalyzed addition of carboxylic acids to terminal alkynes: a high anti-Markovnikov and recoverable homogeneous catalyst.
Re(CO)5Br-catalyzed addition of carboxylic acids to terminal alkynes: a high anti-Markovnikov and recoverable homogeneous catalyst.
The Journal of organic chemistry (2004-08-17)
Ruimao Hua, Xin Tian
PMID15307759
摘要
The addition of carboxylic acids to terminal alkynes is efficiently catalyzed by the early transition-metal complex Re(CO)5Br in toluene or n-heptane at 110 degrees C in an air atmosphere, affording the anti-Markovnikov adducts in good yields with high selectivity. In most cases, the reactions afford unusual Z-adduct predominantly. When n-heptane was used as solvent, Re(CO)5Br can be partly recovered from the reaction mixture.
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