- Enantioselective total synthesis of the indole alkaloid 16-episilicine.
Enantioselective total synthesis of the indole alkaloid 16-episilicine.
Chemical communications (Cambridge, England) (2009-05-14)
Mercedes Amat, Begoña Checa, Núria Llor, Elies Molins, Joan Bosch
PMID19436915
摘要
The first total synthesis of (-)-16-episilicine has been completed from a phenylglycinol-derived bicyclic lactam, the key steps being stereoselective conjugate addition and alkylation reactions, and a ring-closing metathesis.
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