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Merck
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重要文件

V900688

Supelco

异烟肼

Vetec, reagent grade, 98%

同義詞:

4-吡啶羧酸酰肼, INH, 异烟酸肼, 雷米封

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About This Item

經驗公式(希爾表示法):
C6H7N3O
CAS號碼:
分子量::
137.14
Beilstein:
119374
EC號碼:
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:

等級

reagent grade

產品線

Vetec

化驗

98%

mp

171-173 °C (lit.)

形式

neat

SMILES 字串

NNC(=O)c1ccncc1

InChI

1S/C6H7N3O/c7-9-6(10)5-1-3-8-4-2-5/h1-4H,7H2,(H,9,10)

InChI 密鑰

QRXWMOHMRWLFEY-UHFFFAOYSA-N

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生化/生理作用

针对结核菌的抗生素,抑制分枝菌酸的生物合成。由肝脏 N-乙酰转移酶 (NAT) 和 细胞色素 P450 2E1 (CYP2E1) 代谢形成肝毒素。选择性诱导 CYP2E1 的表达。可逆抑制 CYP2C19 和 CYP3A4 的活性,在临床相关浓度下机械性地灭活 CYP1A2、CYP2A6、CYP2C19 和 CYP3A4。

法律資訊

Vetec is a trademark of Merck KGaA, Darmstadt, Germany

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Oral - Skin Irrit. 2

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3


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