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Merck
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重要文件

1356756

USP

拉莫三嗪

United States Pharmacopeia (USP) Reference Standard

同義詞:

6-(2,3-二氯苯基)-1,2,4-三嗪-3,5-二胺, GI 267119X

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About This Item

經驗公式(希爾表示法):
C9H7Cl2N5
CAS號碼:
分子量::
256.09
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

pharmaceutical primary standard

API 家族

lamotrigine

製造商/商標名

USP

應用

pharmaceutical (small molecule)

形式

neat

SMILES 字串

Nc1nnc(c(N)n1)-c2cccc(Cl)c2Cl

InChI

1S/C9H7Cl2N5/c10-5-3-1-2-4(6(5)11)7-8(12)14-9(13)16-15-7/h1-3H,(H4,12,13,14,16)

InChI 密鑰

PYZRQGJRPPTADH-UHFFFAOYSA-N

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生化/生理作用

抗惊厥药。

分析報告

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他說明

USP issued SDS can be found here.
Sales restrictions may apply.

象形圖

Skull and crossbones

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 3 Oral

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Effect of Permeation enhancers on diffusion of lamotrigine drug through cellophane membrane.
Rao, Vinay, et al.
American Journal of Advanced Drug Delivery, 1.4, 606-610 (2013)
Allyson K Friedman et al.
Science (New York, N.Y.), 344(6181), 313-319 (2014-04-20)
Typical therapies try to reverse pathogenic mechanisms. Here, we describe treatment effects achieved by enhancing depression-causing mechanisms in ventral tegmental area (VTA) dopamine (DA) neurons. In a social defeat stress model of depression, depressed (susceptible) mice display hyperactivity of VTA
Mary Ellen Trunko et al.
The International journal of eating disorders, 47(3), 329-334 (2013-12-18)
Some patients with symptoms of binge eating and purging are successfully treated with specific serotonin reuptake inhibitors (SSRIs), but others experience only partial or no benefit. Significant affect dysregulation and poor impulse control may be characteristics that limit responsiveness. We
Frank J E Vajda et al.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 20(1), 13-16 (2012-10-06)
Lamotrigine has been demonstrated to be effective as both an antiepileptic drug and a mood stabiliser. For epilepsy it is less efficacious than valproate in primary generalised epilepsy, but it is comparable to some traditional drugs in partial epilepsy. In
Jennifer L Rosselli et al.
The Annals of pharmacotherapy, 45(1), 108-113 (2010-12-30)
To evaluate the efficacy of lamotrigine for treatment of short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT) syndrome. Literature was accessed through MEDLINE (1950-June 2010) using the terms lamotrigine, triazines, SUNCT, and trigeminal autonomic cephalgia. All articles

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