1084306

Cabergoline

United States Pharmacopeia (USP) Reference Standard

• 同義詞: Cabergoline, 1-Ethyl-3-(3′-dimethylaminopropyl)-3-(6′-allylergoline-8′β-carbonyl)urea, 1-[(6-Allylergoline-8β-yl)carbonyl]-1-[3-(dimethylamino)-propyl]-3-ethylurea, Cabaser, Dostinex, FCE-21336
• 經驗公式（希爾表示法）: C₂₆H₃₇N₅O₂
• CAS號碼: 81409-90-7
• 分子量：: 451.60
• MDL號碼: MFCD00867887
• 分類程式碼代碼: 41116107
• PubChem物質ID: 329749190
• NACRES: NA.24

屬性

• 等級: pharmaceutical primary standard
• API 家族: cabergoline
• 製造商／商標名: USP
• 應用: pharmaceutical (small molecule)
• 形式: neat
• SMILES 字串: CCNC(=O)N(CCCN(C)C)C(=O)[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(CC=C)C1
• InChI: 1S/C26H37N5O2/c1-5-11-30-17-19(25(32)31(26(33)27-6-2)13-8-12-29(3)4)14-21-20-9-7-10-22-24(20)18(16-28-22)15-23(21)30/h5,7,9-10,16,19,21,23,28H,1,6,8,11-15,17H2,2-4H3,(H,27,33)/t19-,21-,23-/m1/s1
• InChI 密鑰: KORNTPPJEAJQIU-KJXAQDMKSA-N
• 基因資訊: human ... DRD2(1813)

描述

一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

生化／生理作用

Cabergoline, a lysergic acid amide derivative, is a potent dopamine D2 receptor agonist. It also acts on dopamine receptors in lactophilic hypothalamus cells to suppress prolactin production in the pituitary gland. It has been used for monotherapy of Parkinson′s disease in the early phase; combination therapy, together with levodopa and a decarboxylase inhibitor such as carbidopa, in progressive-phase Parkinson′s disease and adjunctive therapy of prolactin-producing pituitary gland tumors (microprolactinomas).

Dopamine D2-receptor agonist; Prolactin inhibitor; Antiparkinsonian

分析報告

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他說明

Sales restrictions may apply.

安全資訊

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H302,H362
• 防範說明: P202 - P260 - P263 - P264 - P301 + P312 - P308 + P313
• 危險分類: Acute Tox. 4 Oral - Lact.
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable