BP1141

系统适用性试验用格列美脲

British Pharmacopoeia (BP) Reference Standard

• 同義詞: 格列美脲
• 經驗公式（希爾表示法）: C₂₄H₃₄N₄O₅S
• CAS號碼: 93479-97-1
• 分子量：: 490.62
• MDL號碼: MFCD00878417
• 分類程式碼代碼: 41116107
• NACRES: NA.24

屬性

• 等級: pharmaceutical primary standard
• API 家族: glimepiride
• 形狀: solid
• 儲存期限: limited shelf life, expiry date on the label
• 製造商／商標名: BP
• 應用: pharmaceutical; pharmaceutical small molecule
• 形式: neat
• 儲存溫度: 2-8°C
• SMILES 字串: CCC1=C(C)CN(C(=O)NCCc2ccc(cc2)S(=O)(=O)NC(=O)N[C@H]3CC[C@H](C)CC3)C1=O
• InChI: 1S/C24H34N4O5S/c1-4-21-17(3)15-28(22(21)29)24(31)25-14-13-18-7-11-20(12-8-18)34(32,33)27-23(30)26-19-9-5-16(2)6-10-19/h7-8,11-12,16,19H,4-6,9-10,13-15H2,1-3H3,(H,25,31)(H2,26,27,30)/t16-,19-
• InChI 密鑰: WIGIZIANZCJQQY-RUCARUNLSA-N
• 基因資訊: human ... ABCC8(6833) , KCNJ11(3767)

描述

一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

應用

格列美脲目前用于治疗 2 型糖尿病。

Glimepiride for system suitability BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

生化／生理作用

心脏 K_ATP 通道的强力阻断剂。

格列美脲是一种有效的心肌梗死 K_ATP 通道阻断剂，被吡那地尔激活，IC₅₀ 值为 6.8 nM。

包裝

Unit quantity: 25 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

其他說明

Sales restrictions may apply.

安全資訊

• 象形圖: GHS08
• 訊號詞: Warning
• 危險聲明: H361
• 防範說明: P201 - P202 - P280 - P308 + P313 - P405 - P501
• 危險分類: Repr. 2
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable