推薦產品
材料
stainless steel column
品質等級
agency
suitable for USP L60
產品線
SUPELCOSIL™
特點
endcapped
製造商／商標名
SUPELCOSIL™
包裝
1 ea of
標籤範圍
12.0% carbon loading
參數
≤70 °C temp. limit
400 bar pressure (5801 psi)
技術
HPLC: suitable
長度 × 內徑
25 cm × 3 mm
表面積
170 m2/g
表面覆盖率
surface coverage 3.4 μmol/m2
基質
silica gel, spherical particle platform
fully porous particle
基質活性組
amide, alkyl phase
粒徑
5 μm
孔徑
120 Å
pH值範圍
2-7.5
應用
food and beverages
分離技術
reversed phase
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一般說明
SUPELCOSIL LC-ABZ 相具有独特的去活技术，该可为碱性化合物以及酸性、中性和非极性化合物提供出色的反相性能。不需要采取使用同类胺在高离子强度下运行，以及调节流动相的极端 pH 值来抑制硅烷醇活性，就可以在 LC-ABZ 相上获得良好的峰形。
特點和優勢
• 用于酸性、碱性、两性离子
• 相对于标准反相具有更大的极性保留性
• 独特的选择性
• 硅烷醇去活
• 对于非极性分析物，峰形、柱效和保留性相当于 C8 相
• 相对于标准反相具有更大的极性保留性
• 独特的选择性
• 硅烷醇去活
• 对于非极性分析物，峰形、柱效和保留性相当于 C8 相
法律資訊
SUPELCOSIL is a trademark of Sigma-Aldrich Co. LLC
K Valkó et al.
Journal of pharmaceutical and biomedical analysis, 11(4-5), 361-366 (1993-04-01)
S-Adenosyl-L-methionine (SAM) and its metabolites S-adenosyl-L-homocysteine (SAH) and methyl-thioadenosine (MTA) are endogenous compounds that are heavily involved in a variety of biochemical processes, and have therefore been the target for several assays in body fluids and tissues. Reversed-phase chromatographic behaviour
Q C Li et al.
Journal of chromatographic science, 38(6), 246-254 (2000-07-13)
Nevirapine (Viramune), a dipyridiodiazepinone, is a potent and highly specific nonnucleoside inhibitor of HIV-1 reverse transcriptase. This paper describes the validation of a specific, sensitive, and stability-indicating high-performance liquid chromatography method for the assay and determination of related organic impurities
Murali Pendela et al.
Journal of separation science, 32(20), 3418-3424 (2009-09-19)
Streptomycin (SM) is composed of streptidine, streptose and N-methyl glucosamine sugar moieties. For the determination of SM and its related substances, an ion-pair LC-UV detection method using a Supelcosil LC-ABZ column was developed previously. While analyzing commercial samples, several unknown
D Korakas et al.
Journal of pharmaceutical and biomedical analysis, 12(9), 1141-1145 (1994-09-01)
A series of biologically active peptides and their conjugates with lipidic amino acids were investigated by systematic change of the mobile phase composition using traditional octadecylsilica stationary phase and the newly developed Supelcosil LC-ABZ column. The mobile phases contained various
Ana B Baranda et al.
Journal of chromatography. A, 1031(1-2), 275-280 (2004-04-03)
A high-performance liquid chromatographic method with electrochemical detection was developed for the simultaneous determination of five 1,4-dihydropyridines: amlodipine, nitrendipine, felodipine, lacidipine and lercanidipine. These drugs are widely used in the treatment of hypertension, angina pectoris and the therapy of cerebrovascular
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