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581322-U

Supelco

Ascentis® C18 (3 µm) HPLC Columns

L × I.D. 15 cm × 4.6 mm, HPLC Column

同義詞:

Ascentis RP18 HPLC色谱柱

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About This Item

分類程式碼代碼:
41115700
eCl@ss:
32110501
NACRES:
SB.52

產品名稱

Ascentis ® C18 HPLC 色谱柱, 3 μm particle size, L × I.D. 15 cm × 4.6 mm

材料

stainless steel column

agency

suitable for USP L1 (Similar to Phenomenex Luna C18)

產品線

Ascentis®

特點

endcapped

製造商/商標名

Ascentis®

包裝

1 ea of

標籤範圍

25% Carbon loading

參數

≤70 °C temp. range
400 bar pressure (5801 psi)

技術

HPLC: suitable
LC/MS: suitable

長度 × 內徑

15 cm × 4.6 mm

表面積

450 m2/g

表面覆盖率

3.7 μmol/m2

雜質

<5 ppm metals

基質

fully porous particle
silica gel high purity, spherical

基質活性組

C18 (octadecyl) phase

粒徑

3 μm

孔徑

100 Å

工作pH值範圍

2-8

應用

food and beverages

分離技術

reversed phase

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一般說明

Ascentis 系列色谱柱是 Supelco 科学家推出的第四代 HPLC 色谱柱技术。Ascentis 系列色谱柱是以高纯硅胶为基质,孔径 100Å,硅胶粒径为 3、5 和 10 微米。该色谱柱用于小分子的应用,柱内径可从微径柱(1.0mm 内径)扩展到制备尺寸(50mm 内径)。该系列包括 C18、C8、苯基、Si 和内嵌极性基团相(反相酰胺)。

Ascentis C18 是特别稳定可靠的首选 HPLC 色谱柱,即使对于难以分离的化合物也能提供对称的峰形和出色的保留性能。

應用


  • A dilute-and-shoot liquid chromatography-tandem mass spectrometry method for urinary 18-hydroxycortisol quantification and its application in establishing reference intervals: 本文详细介绍了 Ascentis® C18 色谱柱在临床环境尿液皮质醇水平测量中的应用。该方法为患者激素水平评估提供了一种快速、准确、可靠的方法,对于内分泌失调诊断至关重要(Zhao et al., 2022)。

  • A Comparative Study on Analysis of Ginsenosides in American Ginseng Root Residue by HPLC-DAD-ESI-MS and UPLC-HRMS-MS/MS: 本研究利用Ascentis® C18比较了定量人参皂苷的不同分析方法,展示了该色谱柱在天然产物研究中的适配能力和精确性——这对于确保草药的质量和功效至关重要(Hsu et al., 2022)。

  • Validation of a Rapid and Easy-to-Apply Method to Simultaneously Quantify Co-Loaded Dexamethasone and Melatonin PLGA Microspheres by HPLC-UV: 这项研究重点介绍了Ascentis® C18 在药物制剂中的有效性,证明了其分析复杂药物输送系统的能力,有助于开发更有效的治疗方案(Brugnera et al., 2022)。

  • Simultaneous determination of ivermectin, clorsulon and their related substances in an injectable finished product by a stability-indicating RP-HPLC method: 本文介绍了Ascentis® C18 在兽医学中的应用,提供了有关药物稳定性和成分的重要见解——这对于法规遵从性和动物安全至关重要(Padivitage et al., 2022)。

特點和優勢

  • 出色的保留性能
  • 优良的峰形对称性
  • 重现性好
  • 与 LC-MS 完全兼容

推薦產品

探索最适于 HPLCLC-MS 分析的 LiChropur 试剂

法律資訊

Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析證明 (COA)

Lot/Batch Number

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Dipanjan Goswami et al.
Biomedical chromatography : BMC, 23(11), 1227-1241 (2009-07-14)
A LC-MS/MS method for plasma topiramate analysis is delineated involving least number of healthy volunteers. Topiramate and amlodipine internal standard (IS) were extracted by simple centrifuge-coupled solid-phase extraction and reverse-phase chromatographic separation was performed on an Ascentis C(18) column. Turbo-spray
Federica Pellati et al.
Journal of pharmaceutical and biomedical analysis, 55(5), 934-948 (2011-04-19)
In this study, the composition of polyphenols (phenolic acids and flavonoids) in propolis extracts was investigated by HPLC-DAD and HPLC-ESI-MS/MS by comparing the performance of ion trap and triple quadrupole mass analyzers. The analyses were carried out on an Ascentis
Federica Vacondio et al.
Journal of pharmaceutical and biomedical analysis, 46(1), 200-205 (2007-10-26)
A rapid, simple and sensitive liquid chromatography-mass spectrometry (LC-MS) method was developed and validated for the determination of the imidazole H(3) antagonist ROS203 in rat plasma, using the superior homologue ROS287 as internal standard. Analyses were performed on an Agilent
Federica Pellati et al.
Journal of chromatography. A, 1242, 43-58 (2012-05-09)
In this study, a detailed phytochemical characterization of Echinacea pallida (Nutt.) Nutt. root extracts and dietary supplements was carried out for the first time by developing advanced chromatographic techniques, based on HPLC with diode array (DAD) and electrospray ionization-mass spectrometry
Meiyun Shi et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 951-952, 129-134 (2014-02-22)
Aralia mandshrica is a well-known traditional Chinese medicine from Northeast China commonly used to treat digestive, circulatory and immune system disorders. Calenduloside E is one of its bioactive components currently under evaluation as a pure drug. In this study, a

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