15020AST

Astec^® CHIROBIOTIC^® V2 Chiral (5 μm) HPLC Columns

L × I.D. 25 cm × 2.1 mm, HPLC Column

• 同義詞: TM=["Astec"] TM=["CHIROBIOTIC"] V2 Chiral Chromatography Column
• 分類程式碼代碼: 41115700
• eCl@ss: 32110501
• NACRES: SB.52

屬性

• product name: Astec^® CHIROBIOTIC^® V2手性HPLC色谱柱, 5 μm particle size, L × I.D. 25 cm × 2.1 mm
• 材料: stainless steel column
• 品質等級: 100
• agency: suitable for USP L88
• 描述: HPLC column
• 產品線: Astec^®
• 包裝: pkg of 1 ea
• 製造商／商標名: Astec^®
• 參數: 0-45 °C temperature; 241 bar pressure (3500 psi)
• 技術: HPLC: suitable; LC/MS: suitable
• 長度 × 內徑: 25 cm × 2.1 mm
• 基質: High-purity silica gel particle platform; fully porous particle
• 基質活性組: vancomycin phase
• 粒徑: 5 μm
• 孔徑: 200 Å
• 工作pH值範圍: 3.5-7.0
• 分離技術: chiral

描述

一般說明

中性分子、酰胺、酸、酯和胺对这些基于万古霉素的CSP显示出相当大的对映选择性。在CHIROBIOTIC^® V的极性离子模式下，分离出各种各样的仲胺和叔胺分子。CHIROBIOTIC^® V已经表现出蛋白质固定相的许多分离特性，但同时具有出色的稳定性和更高的样品容量。一些尚未报道在任何其他手性固定相上得到分离的手性分析物被分离出来。CHIROBIOTIC^® V和V2的区别在于键合化学性质与载体颗粒的孔径不同，这赋予它们不同的选择性和制备能力。

• 键合相：万古霉素
• 工作pH范围：3.5 - 7.0
• 粒径：5、10或16 μm
• 孔径：100Å（CHIROBIOTIC^® V）或200Å（CHIROBIOTIC^® V2）

CHIROBIOTIC FAQ
CHIROBIOTIC参考书目
Chiral产品文献

應用

• Development and validation of an UFLC-MS/MS method for enantioselectivity determination of d,l-threo-methylphenidate, d,l-threo-ethylphenidate and d,l-threo-ritalinic acid in rat plasma and its application to pharmacokinetic study.: This study utilizes the Astec^® CHIROBIOTIC^® V2 Chiral HPLC Column to develop and validate a UFLC-MS/MS method for the enantioselective determination of various methylphenidate and ritalinic acid enantiomers in rat plasma. The column′s application in pharmacokinetic studies underscores its effectiveness in biomedical research, particularly in analyzing chiral drug molecules (Zhang et al., 2016).


• New high-performance liquid chromatography method for the determination of (R)-warfarin and (S)-warfarin using chiral separation on a glycopeptide-based stationary phase.: This research employs the Astec^® CHIROBIOTIC^® V2 Chiral HPLC Column for the chiral separation and determination of warfarin enantiomers. The study highlights the column′s utility in pharmaceutical analysis and its effectiveness in the study of chiral drug enantiomers (Malakova et al., 2009).

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法律資訊

Astec is a registered trademark of Merck KGaA, Darmstadt, Germany

CHIROBIOTIC is a registered trademark of Sigma-Aldrich Co. LLC