WH0005607M1

Monoclonal Anti-MAP2K5 antibody produced in mouse

clone M1-E6, purified immunoglobulin, buffered aqueous solution

• 同義詞: Anti-HsT17454, Anti-MAPKK5, Anti-MEK5, Anti-PRKMK5, Anti-mitogen-activated protein kinase kinase 5
• MDL號碼: MFCD01633629
• 分類程式碼代碼: 12352203
• NACRES: NA.41
• 無性繁殖: M1-E6, monoclonal
• application: ELISA (i); IF; WB
• 物種活性: human
• 技術: immunofluorescence: suitable; indirect ELISA: suitable; western blot: 1-5 μg/mL

屬性

• 生物源: mouse
• 品質等級: 100
• 共軛: unconjugated
• 抗體表格: purified immunoglobulin
• 抗體產品種類: primary antibodies
• 無性繁殖: M1-E6, monoclonal
• 形狀: buffered aqueous solution
• 物種活性: human
• 技術: immunofluorescence: suitable; indirect ELISA: suitable; western blot: 1-5 μg/mL
• 同型: IgG1κ
• GenBank登錄號: BC008838
• UniProt登錄號: Q13163
• 運輸包裝: dry ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... MAP2K5(5607)

描述

一般說明

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been described. (provided by RefSeq)

免疫原

MAP2K5 (AAH08838, 1 a.a. ~ 448 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
MLWLALGPFPAMENQVLVIRIKIPNSGAVDWTVHSGPQLLFRDVLDVIGQVLPEATTTAFEYEDEDGDRITVRSDEEMKAMLSYYYSTVMEQQVNGQLIEPLQIFPRACKPPGERNIHGLKVNTRAGPSQHSSPAVSDSLPSNSLKKSSAELKKILANGQMNEQDIRYRDTLGHGNGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVENRISICTEFMDGGSLDVYRKMPEHVLGRIAVAVVKGLTYLWSLKILHRDVKPSNMLVNTRGQVKLCDFGVSTQLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISFMELALGRFPYPQIQKNQGSLMPLQLLQCIVDEDSPVLPVGESSEPFVHFITQCMRKQPKERPAPEELMGHPFIVQFNDGNAAVVSMWVCRALEERRSQQGPP

外觀

Solution in phosphate buffered saline, pH 7.4

法律資訊

GenBank is a registered trademark of United States Department of Health and Human Services

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)