WH0000215M1

Monoclonal Anti-ABCD1 antibody produced in mouse

clone 4B5, purified immunoglobulin, buffered aqueous solution

• 同義詞: Anti-ABC42, Anti-ALD, Anti-ALDP, Anti-AMN, Anti-ATP-binding cassette, sub-family D (ALD), member 1
• MDL號碼: MFCD02262510
• 分類程式碼代碼: 12352203
• NACRES: NA.41
• 共軛: unconjugated
• application: ELISA (i)
• 無性繁殖: 4B5, monoclonal
• 物種活性: human
• 技術: indirect ELISA: suitable

屬性

• 生物源: mouse
• 品質等級: 100
• 共軛: unconjugated
• 抗體表格: purified immunoglobulin
• 抗體產品種類: primary antibodies
• 無性繁殖: 4B5, monoclonal
• 形狀: buffered aqueous solution
• 物種活性: human
• 技術: indirect ELISA: suitable
• 同型: IgG2aκ
• GenBank登錄號: BC015541
• UniProt登錄號: P33897
• 運輸包裝: dry ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... ABCD1(215)

描述

一般說明

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in this gene have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system. (provided by RefSeq)

免疫原

ABCD1 (AAH15541, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
MPVLSRPRPWRGNTLKRTAVLLALAAYGAHKVYPLVRQCLAPARGLQAPAGEPTQEASGVAAAKAGMNRVFLQRLLWLLRLLFPRVLCRETGLLALHSAA

特點和優勢

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外觀

Solution in phosphate buffered saline, pH 7.4

法律資訊

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安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)