化驗
>98%
形狀
solid
顏色
white
溶解度
aqueous buffers below pH 8: 1 mM
DMSO: soluble
ethanol: soluble
SMILES 字串
Cl.OC1CCCCC1N2CCC(CC2)c3ccccc3
InChI
1S/C17H25NO.ClH/c19-17-9-5-4-8-16(17)18-12-10-15(11-13-18)14-6-2-1-3-7-14;/h1-3,6-7,15-17,19H,4-5,8-13H2;1H
InChI 密鑰
XJNUHVMJVWOYCW-UHFFFAOYSA-N
基因資訊
human ... SLC18A3(6572)
生化／生理作用
Potent inhibitor of vesicular acetylcholine storage.
儲存類別代碼
13 - Non Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
Mee-Rye Park et al.
ChemSusChem, 13(17), 4455-4467 (2020-03-12)
There is strong interest in the valorization of lignin to produce valuable products; however, its structural complexity has been a conversion bottleneck. Chemical pretreatment liberates lignin-derived soluble fractions that may be upgraded by bioconversion. Cholinium ionic liquid pretreatment of sorghum
C Prior et al.
General pharmacology, 23(6), 1017-1022 (1992-11-01)
1. Vesamicol (2-[4-phenylpiperidino] cyclohexanol) inhibits the transport of acetylcholine into synaptic vesicles in cholinergic nerve terminals. 2. Recent pharmacological studies of the effects of vesamicol on skeletal neuromuscular transmission have revealed a pattern of activity for the compound consistent with
B A Bahr et al.
Proceedings of the National Academy of Sciences of the United States of America, 83(7), 2267-2270 (1986-04-01)
Transport and storage of acetylcholine by purified Torpedo electric organ synaptic vesicles is blocked by the drug L-trans-2-(4-phenylpiperidino)cyclohexanol (AH-5183). This study sought evidence of a specific receptor for the drug. Highly tritiated L-trans-2-(4-phenyl [3,4-3H] piperidino)-cyclohexanol (L-[3H] AH5183) was synthesized. An
The vesicular acetylcholine transport system.
Marshall,L, et al.
Trends in Neurosciences, 10, 174-174 (1987)
Phedias Diamandis et al.
Nature chemical biology, 3(5), 268-273 (2007-04-10)
The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain cancer. However, the complete repertoire of signaling pathways that governs the
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