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Merck
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重要文件

U9257

Sigma-Aldrich

UbcH9 Conjugating Enzyme human

≥95% (SDS-PAGE), recombinant, expressed in E. coli, buffered aqueous glycerol solution

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About This Item

MDL號碼:
分類程式碼代碼:
12352202
NACRES:
NA.56

重組細胞

expressed in E. coli

品質等級

化驗

≥95% (SDS-PAGE)

形狀

buffered aqueous glycerol solution

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−70°C

基因資訊

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一般說明

Manufactured for Sigma by Boston Biochem., Inc.

生化/生理作用

UbcH9 mediates the conjugation of SUMO-1, SUMO-2, and SUMO-3 to a diverse variety of proteins without the help of an E3 ligase. This E2 conjugating enzyme interacts directly with protein substrates that are modified by SUMOylation, and may help in substrate recognition. UbcH9 is specific for the conjugation of proteins modified by SUMOylation.

外觀

Solution in 50 mM HEPES, pH 7.5, 100 mM NaCl, 10 % glycerol, 1mM TCEP.

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析證明 (COA)

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J M Desterro et al.
FEBS letters, 417(3), 297-300 (1997-12-31)
Ubiquitin conjugating enzymes participate in the thioester cascade that leads to protein ubiquitination. Although Ubc9 is homologous to E2 ubiquitin conjugating enzymes we have shown that it is unable to form a thioester with ubiquitin, but can form a thioester

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