T9950

Tau-352 human

recombinant, expressed in E. coli, ≥90% (SDS-PAGE), lyophilized powder

• 同義詞: Human Tau Protein
• MDL號碼: MFCD07785730
• 分類程式碼代碼: 12352200
• NACRES: NA.32

屬性

• 生物源: human
• 品質等級: 200
• 重組細胞: expressed in E. coli
• 化驗: ≥90% (SDS-PAGE)
• 形狀: lyophilized powder
• 分子量: 36.8 kDa
• UniProt登錄號: P10636
• 應用: cell analysis
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 基因資訊: human ... MAPT(4137)

描述

應用

Tau-352 human is a Tau isoform, variant 0N3R which means it consists of 3 microtubule binding repeats (R) and no amino terminal inserts (N). The product can be utilized for systemic identification of Phosphorylation sites in microtubule-associated protein tau by using checkpoint kinases Chk1 and Chk2 in vitro.

生化／生理作用

Isoform of Tau, variant 0N3R, having 3 microtubule binding repeats (R) and no amino terminal inserts (N).

Tau-383 human belongs to neuronal microtubule-associated protein family that stimulates the microtubule assembly and stability as well as facilitates hyperphosphorylation-induced self-assembly into filaments. Tau protein along with src can upregulate tyrosine kinase activity. Inhibition of Src kinase influences the action of tau on actin rearrangements which in turn impacts the growth-factor-induced actin remodeling.

重構

Lyophilized from MES, pH 6.8, containing NaCl and EGTA. When reconstituted in water to a protein concentration of 1 mg/mL, the resulting buffer will have ~50 mM MES, pH 6.8, 100 mM NaCl, and 0.5 mM EGTA.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Gloves, type N95 (US)