SRP6553

CIRBP/冷诱导 RNA 结合蛋白 人

recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

• 同義詞: A18HNRNP, CIRP
• 分類程式碼代碼: 12352202
• NACRES: NA.32

屬性

• 生物源: human
• 重組細胞: expressed in E. coli
• 化驗: ≥90% (SDS-PAGE)
• 形狀: lyophilized
• 分子量: 20.5 kDa
• 包裝: pkg of 1 mg; pkg of 20 μg
• 雜質: ≤1 EU/μg endotoxin (LAL test)
• UniProt登錄號: Q14011
• 運輸包裝: wet ice
• 儲存溫度: −70°C
• 基因資訊: human ... CIRBP(1153)

描述

一般說明

CIRBP, also known as cold-inducible RNA-binding protein, plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. CIRBP responds to a wide array of cellular stresses, including short wavelength ultraviolet light (UVC), at the transcriptional and post-translational level. It acts as a translational activator. CIRBP can bind the 3′untranslated region of specific transcripts to stabilize them and facilitate their transport to ribosomes for translation. CIRBP affects NF-κB signaling as opposed to IL1B mRNA stability directly.

外觀

Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 0.25 M Imidazole, 20% glycerol.

重構

Detailed reconstitution instructions are sent along with the product

安全資訊

• 象形圖: GHS08,GHS07
• 訊號詞: Danger
• 危險聲明: H315,H319,H360D
• 防範說明: P202 - P264 - P280 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• 危險分類: Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2
• 儲存類別代碼: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable