SRP6125

Glyoxalase I human

recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

• 同義詞: Aldoketomutase, GLO-1 methylglyoxalase, Glx 1, Lactoylglutathione lyase
• 分類程式碼代碼: 12352204
• NACRES: NA.32

屬性

• 生物源: human
• 重組細胞: expressed in E. coli
• 化驗: ≥90% (SDS-PAGE)
• 形狀: liquid
• 分子量: 20.7 kDa (184 aa, 1-184 aa)
• 包裝: pkg of 100 μg
• NCBI登錄號: Q04760
• UniProt登錄號: Q04760
• 運輸包裝: dry ice
• 儲存溫度: −20°C
• 基因資訊: human ... GLO1(2739)

描述

一般說明

GLO1 is involved in the catalysis and formation of S-lactoyl-glutathione from methylglyoxal condensation and reduced glutathione. GLO1 is linked to HLA and is localized to 6p21.3-p21.1, between HLA and the centromere. GLO1 enzyme is abundantly expressed and present in numerous tumor cell lines, in which its concentration is often upregulated ubiquitously. GLO1 is a major susceptible gene for autism in an ethnic Chinese population from Taiwan. GLO1 might be involved in the pathophysiology of mood disorders. GLO1 plays a role in the pathophysiology of mood disorders. Overexpression of GLO1 is associated with kidney tumor.

外觀

1 mg/mL solution in 20 mM Tris-HCl buffer (pH 8.0) containing 1 mM DTT and 10% glycerol.

準備報告

Centrifuge the vial prior to opening.

其他說明

MAEPQPPSGG LTDEAALSCC SDADPSTKDF LLQQTMLRVK DPKKSLDFYT RVLGMTLIQK CDFPIMKFSL YFLAYEDKND IPKEKDEKIA WALSRKATLE LTHNWGTEDD ETQSYHNGNS DPRGFGHIGI AVPDVYSACK RFEELGVKFV KKPDDGKMKG LAFIQDPDGY WIEILNPNKM ATLM

安全資訊

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H319
• 防範說明: P264 - P280 - P305 + P351 + P338 - P337 + P313
• 危險分類: Eye Irrit. 2
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable