推薦產品
生物源
human
重組細胞
expressed in E. coli
化驗
≥95% (SDS-PAGE)
形狀
liquid
效力
<25 units/mg
分子量
27.9 kDa
包裝
pkg of 100 μg
NCBI登錄號
UniProt登錄號
運輸包裝
dry ice
儲存溫度
−70°C
基因資訊
human ... GSTM2(2946)
一般說明
Glutathione S-transferase Mu 2 (GSTM2) belongs to the Glutathione S-Transferase (GST) family of proteins. There are 8 families of GST proteins: alpha, kappa, mu, omega, pi, sigma, theta and zeta, each of which is composed of proteins that have various functions throughout the cell. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are structured in a gene cluster on chromosome 1p13.3 and are proven to be highly polymorphic. These genetic variants can change an individual′s susceptibility to carcinogens and toxins as well as have an effect on the toxicity and efficacy of several drugs.
外觀
0.5 mg/mL solution in 20 mM Tris HCl (pH 8.0) containing 10% glycerol, 0.1 M NaCl and 1 mM DTT.
準備報告
Centrifuge the vial prior to opening.
其他說明
MGSSHHHHHH SSGLVPRGSH MPMTLGYWNI RGLAHSIRLL LEYTDSSYEE KKYTMGDAPD YDRSQWLNEK FKLGLDFPNL PYLIDGTHKI TQSNAILRYI ARKHNLCGES EKEQIREDIL ENQFMDSRMQ LAKLCYDPDF EKLKPEYLQA LPEMLKLYSQ FLGKQPWFLG DKITFVDFIA YDVLERNQVF EPSCLDAFPN LKDFISRFEG LEKISAYMKS SRFLPRPVFT KMAVWGNK
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Sarah Diab et al.
Future medicinal chemistry, 8(3), 271-285 (2016-02-26)
The discovery of small molecules that selectively inhibit Mnks is considered of paramount importance towards deciphering the exact role of these proteins in carcinogenesis and to further validate them as anti-cancer drug targets. However, the dearth of structural information of
Ziyi Yin et al.
Autophagy, 16(5), 900-916 (2019-07-18)
Cells are faced with various stresses during their growth and development, and autophagy is a degradative process in which cells can break down their own components to recycle macromolecules and provide energy under these stresses. For pathogenic fungi that utilize
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