SRP5102

Mortalin (47-end), GST tagged human

recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

• 同義詞: CSA, GRP75, HSPA9, HSPA9B, MGC4500, MOT, MOT2, MTHSP75, PBP74, mot-2
• CAS號碼: 753517-83-8
• 分類程式碼代碼: 12352200
• NACRES: NA.32

屬性

• 生物源: human
• 重組細胞: expressed in baculovirus infected Sf9 cells
• 化驗: ≥70% (SDS-PAGE)
• 形狀: buffered aqueous glycerol solution
• 分子量: ~97 kDa
• NCBI登錄號: NM_004134
• 應用: cell analysis
• 運輸包裝: dry ice
• 儲存溫度: −70°C
• 基因資訊: human ... HSPA9(3313)

描述

一般說明

Mortalin is a mitochondrial chaperone and a member of the heat shock protein 70 family that is constitutively expressed in cells. Mortalin plays a central role in mitochondrial biogenesis through its capacity to direct the import of nuclear-encoded proteins into the mitochondria. Mortalin plays a role in the control of cell proliferation and elevated levels of mortalin have correlated with malignant transformation and poor cancer prognosis. Mortalin can support cancer cell resistance to complement-dependent cytotoxicity. Mortalin expression was decreased in the mitochondrial fraction of neurons from the substantia nigra of Parkinson disease patients.

外觀

Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

準備報告

after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable