SRP4639

BMP-13 human

recombinant, expressed in E. coli, ≥95% (SDS-PAGE)

• 同義詞: CDMP-2, Cartilage-Derived Morphogenetic Protein-2, GDF-6, bone morphogenetic protein 13
• 分類程式碼代碼: 12352202
• NACRES: NA.32

屬性

• 生物源: human
• 重組細胞: expressed in E. coli
• 化驗: ≥95% (SDS-PAGE)
• 形狀: lyophilized
• 效力: 0.5-4 μg/mL ED₅₀ (determined by its ability to induce alkaline phosphatase production by ATDC-5 chondrogenic cells.)
• 分子量: ~27 kDa
• 包裝: pkg of 50 μg
• 儲存條件: avoid repeated freeze/thaw cycles
• 雜質: endotoxin, tested
• NCBI登錄號: Q6KF10
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 基因資訊: human ... GDF6(392255)

描述

一般說明

BMPs (bone morphogenetic proteins) belong to the TGF-β superfamily of structurally related signaling proteins. These ligands mediate numerous physiological processes. BMPs initiate, promote and maintain cartilage and bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. Expression of BMP-13 has been found in the hypertrophic chondrocytes of ossifying long bone centers. Recombinant human BMP-13/CDMP-2 is a 27 kDa homodimeric disulfide-linked protein consisting of two 120 amino acids polypeptide chains.

外觀

Sterile filtered and Lyophilized without additives.

重構

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.

Reconstitute to 0.1-1.0 mg/mL in water containing BSA (50 μg BSA per 1 μg of protein).