SRP4633

VEGF-C human

recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

• 同義詞: VEGFC, Vascular Endothelial Growth Factor-C
• MDL號碼: MFCD03458368
• 分類程式碼代碼: 12352202
• NACRES: NA.32

屬性

• 生物源: human
• 重組細胞: expressed in E. coli
• 化驗: ≥90% (SDS-PAGE)
• 形狀: lyophilized
• 分子量: 15-16 kDa
• 包裝: pkg of 10 μg
• 儲存條件: avoid repeated freeze/thaw cycles
• 雜質: endotoxin, tested
• NCBI登錄號: Q6FH59
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 基因資訊: human ... VEGFC(7424)

描述

一般說明

The recombinant VEGF-C (vascular endothelial growth factor-C) is a 125 amino acid protein that lacks the N-terminal signal peptide (from T103 to R227 of Gene Bank U58111). Human VEGF-C exhibits about 85% homology with mouse VEGF-C. The VEGFC gene is mapped to human chromosome 4q34.3.

應用

VEGF-C human has been used to determine cell proliferation and survival.

生化／生理作用

VEGF-C (vascular endothelial growth factor-C) promotes tumorigenesis, by inducing lymphatic metastasis. The production of VEGF-C is stimulated by pro-fibrotic transforming growth factor β. The main function of VEGF-C is to mediate lymphangiogenesis. Overexpression of VEGF-C in keratinocytes of skin causes dermal lymphatic vessel hyperplasia.

外觀

Lyophilized without additives.

重構

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.

Reconstitute in 0.1% acetic acid to a concentration of 0.1-1.0 mg/mL.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable