SRP4561

Resistin from rat

recombinant, expressed in E. coli, ≥95% (SDS-PAGE)

• 同義詞: ADSF, Adipose tissue-specific secretory factor, C/EBP-ε-regulated myeloid-specific secreted cysteine-rich protein, Cysteine-rich secreted protein A12-α-like 2, Cysteine-rich secreted protein FIZZ3, RSTN
• MDL號碼: MFCD03792461
• 分類程式碼代碼: 12352200
• NACRES: NA.32

屬性

• 生物源: rat
• 重組細胞: expressed in E. coli
• 化驗: ≥95% (SDS-PAGE)
• 形狀: lyophilized
• 分子量: ~11.9 kDa
• 包裝: pkg of 25 μg
• 雜質: endotoxin, tested
• NCBI登錄號: NP_653342
• UniProt登錄號: Q8CJE0
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 基因資訊: rat ... Retn(246250)

描述

一般說明

Resistin is a new member to of the family of adipocyte-secreted proteins. The biological functions of resistin, as well as its molecular target, are largely unknown. Whether it promotes or antagonizes insulin action is still unclear. Recombinant rat Resistin is an 11.9 kDa protein consisting of 94 amino acid residues and 16 additional amino acids residues-His Tag.
Resistin is an adipocytokine secreted by fat tissues and is localized to pancreatic α-cells in rat.

應用

Resistin from rat has been used to study the effect of resistin on gonadotropins and local ovarian hormone-induced steroidogenesis.

生化／生理作用

Resistin mediates energy homeostasis and inflammation process. Upregulation of resistin is observed in obesity. It is also known to increase blood glucose level and might promote insulin resistance. Thus, it might influence type 2 diabetes. Resistin might be linked to insulin resistance mediated myocardial infarction (MI). In rats, overexpression of resistin is observed in myocardial infarction and cardiac dysfunction.

外觀

Lyophilized from 20 mM Tris, pH 8.0.

重構

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.

Reconstitute in water to a concentration of 0.1-1.0 mg/mL. This solution can then be diluted into other aqueous buffers.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable