推薦產品
生物源
rat
重組細胞
expressed in E. coli
化驗
≥98% (HPLC)
≥98% (SDS-PAGE)
形狀
lyophilized
效力
≤0.1 ng/mL
分子量
6.2 kDa
包裝
pkg of 100 μg
技術
cell culture | mammalian: suitable
雜質
<0.1 EU/μg endotoxin, tested
顏色
white to off-white
1 of 4
本產品 | SML3206 | SML0184 | PHL89743 |
---|---|---|---|
Panax notoginseng (Burk.) F.H.Chen | - | - | - |
powder | powder | powder | solid |
metabolomics | - | - | - |
100 | 100 | 100 | - |
2-8°C | −20°C | 2-8°C | 2-8°C |
一般說明
Epidermal growth factor (EGF) is a potent growth factor and a cytoprotective peptide.[1] Recombinant rat EGF is a 6.2kDa globular protein containing 54 amino acid residues, including 3 intramolecular disulfide-bonds.
應用
Epidermal growth factor (EGF) is used in hepatocyte culture to determine the optimal condition for survival and function of rat hepatocytes.
生化/生理作用
Epidermal growth factor (EGF) stimulates the proliferation of various epidermal and epithelial cells. Additionally, EGF has been shown to inhibit gastric secretion, inflammation and is involved in wound healing.[2][3][1] EGF signals through a receptor known as c-erbB, which is a class I tyrosine kinase receptor.[4] This receptor also binds with TGF-α (transforming growth factor-α) and VGF (vaccinia virus growth factor).
序列
MNSNTGCPPS YDGYCLNGGV CMYVESVDRY VCNCVIGYIG ERCQHRDLRW WKLR
外觀
Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate, pH 7.5.
重構
Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
The role of epidermal growth factor in prevention of oxidative injury and apoptosis induced by intestinal ischemia/reperfusion in rats.
Acta Histochemica, 116(1), 167-175 (2014)
Epidermal growth factor improves survival and prevents intestinal injury in a murine model of pseudomonas aeruginosa pneumonia.
Shock, 36(4), 381-389 (2011)
The epidermal growth factor receptor family: biology driving targeted therapeutics.
Cellular and Molecular Life Sciences, 65(10), 1566-1584 (2008)
PloS one, 5(12), e15914-e15914 (2011-01-07)
Spinal cord injury (SCI) is a widely spread pathology with currently no effective treatment for any symptom. Regenerative medicine through cell transplantation is a very attractive strategy and may be used in different non-exclusive ways to promote functional recovery. We
Epidermal growth factor.
The Journal of biological chemistry, 265(14), 7709-7712 (1990-05-15)
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