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Merck
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重要文件

SRP2112

Sigma-Aldrich

TFIIB, GST tagged human

recombinant, expressed in E. coli, ≥70% (SDS-PAGE)

同義詞:

TF2B, TFIIB

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About This Item

分類程式碼代碼:
12352202
NACRES:
NA.26

生物源

human

重組細胞

expressed in E. coli

化驗

≥70% (SDS-PAGE)

形狀

frozen liquid

分子量

~61.2 kDa

包裝

pkg of 10 μg

儲存條件

avoid repeated freeze/thaw cycles

濃度

400 μg/mL

顏色

clear colorless

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−70°C

基因資訊

human ... GTF2B(2959)

生化/生理作用

The transcription factor IIB (TFIIB) is an essential factor for transcription by RNA polymerase II. TFIIB has been shown to be required for selective binding of RNA polymerase II, TFIIF and TFIID-DNA complex, and for specifying the start site of transcription. Human TFIIB is a single, 35 kDa polypeptide, homologous to yeast factor, the product of the SUA7 gene.

外觀

Clear and colorless frozen liquid solution

準備報告

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. While working, please keep sample on ice.

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析證明 (COA)

Lot/Batch Number

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General initiation factors for RNA polymerase II.
R C Conaway et al.
Annual review of biochemistry, 62, 161-190 (1993-01-01)
The general transcription factors of RNA polymerase II.
G Orphanides et al.
Genes & development, 10(21), 2657-2683 (1996-11-01)
S Malik et al.
Proceedings of the National Academy of Sciences of the United States of America, 88(21), 9553-9557 (1991-11-01)
Transcription factor TFIIB is a ubiquitous factor required for transcription initiation by RNA polymerase II. Previous studies have suggested that TFIIB serves as a bridge between the "TATA"-binding factor (TFIID) and RNA polymerase II during preinitiation complex assembly and, more

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