SML3655

LockdownPro

≥97% (HPLC)

• 同義詞: Tetraethyl 4,4′-((propane-2,2-diylbis(4,1-phenylene))bis(oxy))diphthalate
• 經驗公式（希爾表示法）: C₃₉H₄₀O₁₀
• 分子量：: 668.73
• 分類程式碼代碼: 12352200
• NACRES: NA.25

屬性

• 品質等級: 100
• 化驗: ≥97% (HPLC)
• 形狀: (oil or liquid)
• 顏色: colorless to yellow
• 儲存溫度: 2-8°C
• SMILES 字串: CC(C1=CC=C(C=C1)OC2=CC(C(OCC)=O)=C(C(OCC)=O)C=C2)(C3=CC=C(OC4=CC(C(OCC)=O)=C(C(OCC)=O)C=C4)C=C3)C
• InChI: 1S/C39H40O10/c1-7-44-35(40)31-21-19-29(23-33(31)37(42)46-9-3)48-27-15-11-25(12-16-27)39(5,6)26-13-17-28(18-14-26)49-30-20-22-32(36(41)45-8-2)34(24-30)38(43)47-10-4/h11-24H,7-10H2,1-6H3
• InChI 密鑰: ROEOSYBNNXMANC-UHFFFAOYSA-N

描述

生化／生理作用

Cell permeable, potent, and selective allosteric inhibitor of phosphatase PPM1F that inhibits tissue invasion by PPM1F-overexpressing human cancer cells

LockdownPro, an esterified lockdown analog with better cell permeability, is a cell permeable, potent, and selective allosteric inhibitor of phosphatase PPM1F. LockdownPro potently inhibits tissue invasion by PPM1F-overexpressing human cancer cells. It does not inhibit PPM1F in vitro.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable