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生化/生理作用
CAY10444 is a selective sphingosine-1-phosphate (S1P) receptor 3 (S1P3; EDG3) antagonist that inhibits 1 µM S1P-induced calcium mobilization in HeLa transfectants that express S1P3 over those expressing S1P1/CD363/EDG1 (37.6% vs 6.92% inhibition by 10 µM CAY10444).
Selective sphingosine-1-phosphate (S1P) receptor 3 (S1P3; EDG3) antagonist.
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
Yuuki Koide et al.
Journal of medicinal chemistry, 45(21), 4629-4638 (2002-10-04)
Sphingosine-1-phosphate (S1P) is an intracellular second messenger and an extracellular mediator through endothelial differentiation gene (EDG) receptors, which are a novel class of G-protein-coupled receptors. Although EDG has attracted much attention because of its various roles, no selective agonists or
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