推薦產品
品質等級
化驗
≥95% (HPLC)
形狀
powder
顏色
white to beige
溶解度
DMSO: 2 mg/mL, clear
儲存溫度
-10 to -25°C
SMILES 字串
O[C@H]1C[C@@H]2[C@](CCC(=O)C2(C)C)(C3=C1[C@]4([C@@]([C@H](CC4=O)[C@@H](CC(=O)CC(C)C(=O)O)C)(CC3=O)C)C)C
InChI 密鑰
YTVGSCZIHGRVAV-IYAQLQCNSA-N
生化/生理作用
Ganoderic acid D is one of major triterpenes isolated from Ganoderma lucidum that exhibit potent anticancer properties. Ganoderic acid D inhibits the energy reprogramming of colon cancer cells including glucose uptake, lactate, and pyruvate and acetyl-coenzyme production through SIRT3 upregulation via acetylated cyclophilin D inhibition.
Major triterpenes isolated from Ganoderma lucidum that exhibit potent anticancer properties
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
Zhendong Liu et al.
European journal of pharmacology, 824, 72-77 (2018-01-29)
Ganoderic acid D (GAD) is a highly oxygenated tetracyclic triterpenoid. This study aims to assess the effects of GAD on the energy metabolism of colon cancer through the regulation of SIRT3 expression and whether this effect is related to acetylated
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