SML3503

EN523

≥98% (HPLC)

• 同義詞: 1-(5-Methyl-2-furanyl)-4-(1-oxo-2-propen-1-yl)-2-piperazinone
• 經驗公式（希爾表示法）: C₁₂H₁₄N₂O₃
• CAS號碼: 2094893-05-5
• 分子量：: 234.25
• MDL號碼: MFCD32859220
• 分類程式碼代碼: 12352200
• NACRES: NA.77

屬性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: white to beige
• 溶解度: DMSO: 2 mg/mL, clear
• 儲存溫度: 2-8°C
• SMILES 字串: O=C1N(CCN(C1)C(C=C)=O)C2=CC=C(O2)C
• InChI: 1S/C12H14N2O3/c1-3-10(15)13-6-7-14(11(16)8-13)12-5-4-9(2)17-12/h3-5H,1,6-8H2,2H3
• InChI 密鑰: KYXPDOMFYBFXKO-UHFFFAOYSA-N

描述

生化／生理作用

EN523 is a cell-permeable covalent ligand that selectively modifies a non-catalytic, allosteric cysteine C23 in the K48 ubiquitin-specific deubiquitinase OTUB1. EN523 does not inhibit OTUB1 deubiquitination activity and serves as OTUB1 recruiter.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable