SML3424

DIM-C-pPhOH

≥98% (HPLC)

• 同義詞: 1,1-Bis(3′-indolyl)-1-(p-hydroxyphenyl)methane, 4-(Di-1H-indol-3-ylmethyl)phenol; (4-Hydroxyphenyl)bis(1H-indol-3-yl)methane, 7,7-Bis(3-indolyl)-p-cresol, C-DIM 8, CDIM8
• 經驗公式（希爾表示法）: C₂₃H₁₈N₂O
• CAS號碼: 151358-47-3
• 分子量：: 338.40
• MDL號碼: MFCD03723253
• 分類程式碼代碼: 12352200

屬性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: off-white to pink
• 溶解度: DMSO: 2 mg/mL
• 儲存溫度: −20°C
• SMILES 字串: OC1=CC=C(C(C2=CNC3=C2C=CC=C3)C4=CNC5=C4C=CC=C5)C=C1

描述

生化／生理作用

DIM-C-pPhOH is a NR4A1 (Nur77) antagonist that exhibit potent anticancer activity in pancreatic, colon, breast, kidney, and rhabdomyosarcoma cells. DIM-C-pPhOH decreases expression of PAX3-FOXO1A and β1-integrin proteins in Rh30 rhabdomyosarcoma and MDA-MB-231breast cancer cells. DIM-C-pPhOH inhibits migration of Rh30 and MDA-MB-231 cancer cells.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable