推薦產品
品質等級
化驗
≥98% (HPLC)
形狀
powder
儲存條件
desiccated
顏色
white to beige
溶解度
H2O: 2 mg/mL, clear (warmed)
儲存溫度
−20°C
SMILES 字串
B(O)(O)c1ccc(cc1)CS\C(=N/[H])\N.Br
InChI
1S/C8H11BN2O2S.BrH/c10-8(11)14-5-6-1-3-7(4-2-6)9(12)13;/h1-4,12-13H,5H2,(H3,10,11);1H
InChI 密鑰
PAFZAMOVHIRQOD-UHFFFAOYSA-N
生化/生理作用
BC-11 is a potent and selective inhibitor of urokinase (urokinase-plasminogen activator, uPA). BC-11 inhibits clot lysis with no effect on clot formation. BC-11 exhibits anti-fibrotic activity and improves wound healing and scar quality after topical administration in mice.
potent and selective inhibitor of urokinase (urokinase-plasminogen activator, uPA)
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
Alessandra Longo et al.
Molecules (Basel, Switzerland), 20(6), 9879-9889 (2015-06-02)
BC-11 is an easily synthesized simple thiouronium-substituted phenylboronic acid, which has been shown to be cytotoxic on triple negative MDA-MB231 breast cancer cells by inducing a perturbation of cell cycle when administered at a concentration equal to its ED50 at
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