SML3334

Ceefourin 1

≥95% (HPLC)

• 同義詞: 5-[(2-Benzothiazolylthio)methyl]-2,4-dihydro-4-methyl-3H-1,2,4-triazole-3-thione, Ceefourin-1
• 經驗公式（希爾表示法）: C₁₁H₁₀N₄S₃
• CAS號碼: 315702-40-0
• 分子量：: 294.42
• MDL號碼: MFCD02329957
• 分類程式碼代碼: 12352200
• NACRES: NA.77

屬性

• 品質等級: 100
• 化驗: ≥95% (HPLC)
• 形狀: powder
• 顏色: white to beige
• 溶解度: DMSO: 2 mg/mL, clear
• 儲存溫度: -10 to -25°C
• SMILES 字串: CN1C(CSC2=NC3=C(C=CC=C3)S2)=NNC1=S

描述

生化／生理作用

Ceefourin 1 is a potent and highly selective MRP4 (Multidrug resistance protein 4) inhibitor that exhibits low cellular toxicity and high microsomal and acid stability. Ceefourin 1 inhibits PDAC (pancreatic ductal adenocarcinoma) cell proliferation through MRP4-dependent cAMP extrusion thereby activation of the cAMP/Epac/Rap1 signaling pathway.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable