SML3124

Gemcabene

≥98% (HPLC)

• 同義詞: 6,6′-Oxybis(2,2-dimethylhexanoic acid), CI-1027, PD72953
• 經驗公式（希爾表示法）: C₁₆H₃₀O₅
• CAS號碼: 183293-82-5
• 分子量：: 302.41
• MDL號碼: MFCD00951832
• 分類程式碼代碼: 51111800
• NACRES: NA.77

屬性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: white to beige
• 溶解度: DMSO: 2 mg/mL, clear
• 儲存溫度: 2-8°C
• SMILES 字串: O=C(O)C(CCCCOCCCCC(C(O)=O)(C)C)(C)C
• InChI: 1S/C16H30O5/c1-15(2,13(17)18)9-5-7-11-21-12-8-6-10-16(3,4)14(19)20/h5-12H2,1-4H3,(H,17,18)(H,19,20)
• InChI 密鑰: SDMBRCRVFFHJKR-UHFFFAOYSA-N

描述

生化／生理作用

Gemcabene is an orally available lipid-regulating compound that induces both a cholesterol and triglyceride reduction by a mechanism of action not linked to agonist or antagonist activity on the PPAR-α receptors. Gemcabene down-regulates apoC-III expression. Gemcabene is primarily metabolized (glucuronidation) by UDP-glucuronosyltransferase2B7 (UGT2B7). Thus, is often used as a UGT2B7 substrate.

orally available lipid-regulating compound that induces both a cholesterol and triglyceride reduction

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable