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Merck
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Key Documents

SML2947

Sigma-Aldrich

Penehyclidine hydrochloride

≥98% (HPLC)

同義詞:

α-[(1-Azabicyclo[2.2.2]oct-3-yloxy)methyl]-α-cyclopentyl-benzenemethanol hydrochloride, 3-(2′-phenyl-2′-cyclopentyl-2′-hydroxyl-ethoxy) quinuclidine, Penequine hydrochloride, Penequinine

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About This Item

經驗公式(希爾表示法):
C20H29NO2 · HCl
CAS號碼:
分子量::
351.91
MDL號碼:
分類程式碼代碼:
12352200

品質等級

化驗

≥98% (HPLC)

形狀

powder (hygroscopic)

儲存條件

desiccated

顏色

white to beige

溶解度

H2O: 2 mg/mL, clear

儲存溫度

−20°C

InChI

1S/C20H29NO2.ClH/c22-20(18-8-4-5-9-18,17-6-2-1-3-7-17)15-23-19-14-21-12-10-16(19)11-13-21;/h1-3,6-7,16,18-19,22H,4-5,8-15H2;1H

InChI 密鑰

DDTVVMRZNVIVQM-UHFFFAOYSA-N

生化/生理作用

Penehyclidine hydrochloride is a brain penetrant anticholinergic drug that exhibits both antimuscarinic and antinicotinic activity. Penehyclidine hydrochloride does not induce muscarinic 2 receptor-associated cardiovascular side effects. Penehyclidine hydrochloride is effective in experimental models of heart, lung and brain ischemia reperfusion injury.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Yong-An Wang et al.
Life sciences, 78(2), 210-223 (2005-09-13)
Previous studies have paid little attention to the anticonvulsant effect of anticholinergic drugs that act on both muscarinic (M) and nicotinic (N) receptors during soman-induced seizures. Therefore, with the establishment of a soman-induced seizures model in rats, this study evaluated

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