SML2789

tBPC

≥98% (HPLC)

• 同義詞: 2-[4-(1,1-Dimethylethyl)phenoxy]cyclohexanol
• 經驗公式（希爾表示法）: C₁₆H₂₄O₂
• CAS號碼: 1942-71-8
• 分子量：: 248.36
• MDL號碼: MFCD00155433
• 分類程式碼代碼: 12352200
• NACRES: NA.77

屬性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: white to beige
• 溶解度: DMSO: 2 mg/mL, clear
• 儲存溫度: 2-8°C
• InChI: 1S/C16H24O2/c1-16(2,3)12-8-10-13(11-9-12)18-15-7-5-4-6-14(15)17/h8-11,14-15,17H,4-7H2,1-3H3
• InChI 密鑰: FTIXUILRMBSXNS-UHFFFAOYSA-N

描述

生化／生理作用

tBPC is a postitive allosteric modulator of the neuropeptide Y (NPY) Y4 receptor, which is predominantly expressed in the gastrointestinal tract and activated most strongly by pancreatic polypeptide (PP). tBPC was shown to potentiate Y4R activity in G-Protein signaling and arrestin3 recruitment and to potentiate the native PP response. tBPC was selective for Y4R over other Neuropeptide Y receptors and showed no effect on the efficacy (E_max) or potency (EC₅₀) of the NPY signal response at the Y1, Y2, or Y5 receptors at 30 μM.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3