跳轉至內容
Merck
全部照片(1)

重要文件

檢視所有文件

SML2650

Sigma-Aldrich

T3-CLK

≥98% (HPLC)

同義詞:

4-(2-Methyl-1-(4-methylpiperazin-1-yl)-1-oxopropan-2-yl)-N-(6-(pyridin-4-yl)imidazo[1,2-a]pyridin-2-yl)benzamide, 4-[1,1-Dimethyl-2-(4-methyl-1-piperazinyl)-2-oxoethyl]-N-[6-(4-pyridinyl)imidazo[1,2-a]pyridin-2-yl]benzamide, T3

登入查看組織和合約定價
全部照片(1)

About This Item

經驗公式（希爾表示法）:
C28H30N6O2
CAS號碼:
2109805-56-1
分子量：:
482.58
MDL號碼:
MFCD31689325
分類程式碼代碼:
12352200
NACRES:
NA.77

品質等級

100

化驗

≥98% (HPLC)

形狀

powder

顏色

white to beige

溶解度

DMSO: 2 mg/mL, clear (warmed)

儲存溫度

room temp

SMILES 字串

[n]21c(nc(c2)NC(=O)c4ccc(cc4)C(C)(C)C(=O)N5CCN(CC5)C)ccc(c1)c3ccncc3

InChI

1S/C28H30N6O2/c1-28(2,27(36)33-16-14-32(3)15-17-33)23-7-4-21(5-8-23)26(35)31-24-19-34-18-22(6-9-25(34)30-24)20-10-12-29-13-11-20/h4-13,18-19H,14-17H2,1-3H3,(H,31,35)

InChI 密鑰

IEFFSHLHNYVSEF-UHFFFAOYSA-N

生化／生理作用

T3-CLK (T3) is a cell permeable, highly potent and selective cell-base stable inhibitor of CDC-like kinase (CLK) that exhibits dose-dependent alternative splicing effects in HCT116 colorectal cancer cells. T3-CLK increases conjoined gene (CG) transcription.
cell permeable, highly potent and selective cell-base stable inhibitor of CDC-like kinase (CLK)

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

從最近期的版本中選擇一個：

分析證明 (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our 文件 section.

如果您需要協助，請聯絡 客戶支援

已經擁有該產品？

您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

Tyler Funnell et al.
Nature communications, 8(1), 7-7 (2017-02-25)
CDC-like kinase phosphorylation of serine/arginine-rich proteins is central to RNA splicing reactions. Yet, the genomic network of CDC-like kinase-dependent RNA processing events remains poorly defined. Here, we explore the connectivity of genomic CDC-like kinase splicing functions by applying graduated, short-exposure

我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.

聯絡技術服務