SML2187

RL5a

≥98% (HPLC)

• 同義詞: N2-[2-(2-Furanyl)-4-quinolinyl]-N1,N1-dimethyl-1,2-ethanediamine
• 經驗公式（希爾表示法）: C₁₇H₁₉N₃O
• CAS號碼: 133671-66-6
• 分子量：: 281.35
• MDL號碼: MFCD00929354
• 分類程式碼代碼: 12352200
• NACRES: NA.77

屬性

• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: white to very dark brown
• 溶解度: DMSO: 2 mg/mL, clear
• 儲存溫度: 2-8°C
• SMILES 字串: N(CCNc1c2c(nc(c1)c3[o]ccc3)cccc2)(C)C
• InChI: 1S/C17H19N3O/c1-20(2)10-9-18-15-12-16(17-8-5-11-21-17)19-14-7-4-3-6-13(14)15/h3-8,11-12H,9-10H2,1-2H3,(H,18,19)
• InChI 密鑰: CRGKLHXVNVZAPA-UHFFFAOYSA-N

描述

生化／生理作用

RL5a is a potent inhibitor of the replication licensing system in human cells. RL5a blocks the binding of the origin recognition complex (ORC) to origin DNA, which is required interaction for licensing. RL5a appears to act as noncompetitive inhibitor of ORC with respect to ATP.

potent inhibitor of the replication licensing system.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3