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Merck
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重要文件

SML2023

Sigma-Aldrich

UCSF924NC

≥98% (HPLC)

同義詞:

6-Methyl-2-((3-(pyridin-4-yl)propylamino)methyl)quinolin-4(1H)-one

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About This Item

經驗公式(希爾表示法):
C19H21N3O
CAS號碼:
分子量::
307.39
分類程式碼代碼:
51111800
NACRES:
NA.77

化驗

≥98% (HPLC)

形狀

powder

顏色

white to beige

溶解度

DMSO: 2 mg/mL, clear

儲存溫度

−20°C

SMILES 字串

CC1=CC2=C(NC(CNCCCC3=CC=NC=C3)=CC2=O)C=C1

生化/生理作用

Negative control for the dopamine D4 receptor (DRD4) partial agonist UCSF924.
UCSF924NC (Compound 9-6-16; ZINC000091707446) is the recommended negative control compound for the high-affinity dopamine D4 receptor (DRD4) partial agonist UCSF924 (Compound 9-6-24; ZINC000091726127). UCSF924NC exhibits a 1/2500-fold reduced D4 affinity when compared with that of UCSF924.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析證明 (COA)

Lot/Batch Number

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Sheng Wang et al.
Science (New York, N.Y.), 358(6361), 381-386 (2017-10-21)
Dopamine receptors are implicated in the pathogenesis and treatment of nearly every neuropsychiatric disorder. Although thousands of drugs interact with these receptors, our molecular understanding of dopaminergic drug selectivity and design remains clouded. To illuminate dopamine receptor structure, function, and

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