SML0804

(S)-CPP sodium salt

≥96% (HPLC)

• 同義詞: (S)-2-Chloro-3-phenylpropanoic acid sodium salt, (aS)-a-chloro-benzenepropanoic acid sodium salt
• 經驗公式（希爾表示法）: C₉H₈ClO₂ · Na
• CAS號碼: 194979-70-9
• 分子量：: 206.60
• MDL號碼: MFCD28118980
• 分類程式碼代碼: 12352200
• PubChem物質ID: 329825602
• NACRES: NA.77

屬性

• 品質等級: 100
• 化驗: ≥96% (HPLC)
• 形狀: powder
• 顏色: white to beige
• 溶解度: H₂O: 20 mg/mL, clear
• 儲存溫度: 2-8°C
• SMILES 字串: [O-]C([C@@H](Cl)CC1=CC=CC=C1)=O.[Na+]
• InChI: 1S/C9H9ClO2.Na/c10-8(9(11)12)6-7-4-2-1-3-5-7;/h1-5,8H,6H2,(H,11,12);/q;+1/p-1/t8-;/m0./s1
• InChI 密鑰: HMHPCHNNVOLTFC-QRPNPIFTSA-M

描述

生化／生理作用

(S)-CPP is an inhibitor of branched-chain α-ketoacid dehydrogenase complex (BCKDC) kinase, also know as BDK, or keto acid dehydrogenase kinase. BDK is a negative regulator of BCKDC activity. Inhibition of BDK by (S)-CPP (IC₅₀ = 6.3 μM) leads to complex activation, and significant reduction of plasma levels of leucine/isoleucine and valine in wild type mice.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable