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Key Documents

SML0563

Sigma-Aldrich

Docosahexaenoyl ethanolamide

≥98% (HPLC), ethanol solution (5 mg/ml)

同義詞:

DEA, DHEA

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About This Item

經驗公式(希爾表示法):
C24H37NO2
CAS號碼:
分子量::
371.56
分類程式碼代碼:
12352211
NACRES:
NA.77

品質等級

化驗

≥98% (HPLC)

形狀

ethanol solution (5 mg/ml)

藥物控制

regulated under CDSA - not available from Sigma-Aldrich Canada

顏色

colorless to yellow

運輸包裝

dry ice

儲存溫度

−20°C

生化/生理作用

Docosahexaenoyl ethanolamide (DHEA) has the ability to block the proliferation of head and neck squamous cell carcinoma (HNSCC) cell.
Docosahexaenoyl ethanolamide (DHEA) is a lipid signaling molecule present in brain and retina at concentrations, similar to those for arachidonoyl ethanolamide. DHEA binds to the rat brain CB1 receptor with a Ki of 324 nM. It exhibits anti-inflammatory and organ protective activity. Studies show that docosahexaenoyl ethanolamide is the mediator of neurite growth and synaptogenesis in hippocampal neurons, resulting in enhanced synaptic activity.

特點和優勢

This compound is featured on the Cannabinoid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

象形圖

FlameExclamation mark

訊號詞

Danger

危險聲明

危險分類

Eye Irrit. 2 - Flam. Liq. 2

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

55.4 °F

閃點(°C)

13 °C


分析證明 (COA)

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存取文件庫

5-lipoxygenase mediates docosahexaenoyl ethanolamide and N-arachidonoyl-L-alanine-induced reactive oxygen species production and inhibition of proliferation of head and neck squamous cell carcinoma cells
Park SW, et al.
BMC Cancer, 16(1), 458-458 (2016)

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